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1.  Review Article
Platelet rich fibrin: New treatment modality in Grade II furcation defects
Dhruv Mehta, Neeraj Deshpande, Deepak Dave, Bhavesh Modi, Ashit Bharwani
Full Text PDF | Abstract | No of Hits : 1598


Plateletrich rich fibrin (PRF) is an autologous healing biomaterial, which incorporates a matrix of autologous fibrin, leukocytes, platelets and growth factors, harvested from a simple blood sample. Various growth factors present in PRF are well-known source of cytokines, usable for clinical applications. Grade II furcation lesion is essentially a cul-de-sac with a definite horizontal component and involvement of the interradicular bone without a through-and-through ability to probe. Furcation defects represent a formidable problem in the treatment of periodontal disease, which is related to the complex and irregular anatomy of furcation. The early Grade II furcation requires surgical management. Surgery permits access for root debridement, odontoplasty, osseous recontouring, and periodontal regeneration. Regeneration of the previously destroyed periodontal attachment tissues is biologically possible, and the regeneration has become the goal of therapy since the 1990s. Regenerative attempts such as bone grafts, guided tissue regeneration, application of growth factors, and enamel matrix derivatives are currently used for periodontal regeneration in the treatment of Grade II furcation involvements which under favorable conditions, can induce roughly 60-70% regeneration of the bone lesion’s height or volume, with concomitant improvement in the clinical conditions. This review will help in understanding regenerative property of PRF in furcation defects.

Keywords Grade II furcation, periodontal regeneration, platelet concentrate, plateletrich fibrin

How to cite this article: Mehta D, Deshpande N, Dave D, Modi B, Bharwani A. Platelet rich fibrin: New treatment modality in Grade II furcation defects. J Oral Dis Market 2016;1:1-5.

2.  Review Article
Human herpes virus: Bacteria and periodontium
Akta Sanghavi, Deepak Dave, Prasad Nadig, Tulsi Sanghavi, Nirali Khanpara
Full Text PDF | Abstract | No of Hits : 981


Periodontitis is a chronic inflammatory disease with complex aetiopathogenesis. It is associated with the biofilm, which has primary role in the development of periodontitis and has a slow to rapid destruction may be observed. Many different factors have been involved in the initiation of periodontitis, including gene polymorphism, bacterial, immunological and environmental causes. Recently, in periodontitis patients viruses were detected. Studies reported high count of Epstein–Barr virus, human herpes simplex-1 and Human cytomegalovirus in aggressive and chronic periodontitis, it is unlikely that these herepes viruses are acting merely as innocuous bystanders in periodontal disease. These human Herpes viruses cooperate with specific bacteria in periodontal tissue breakdown so they probably not stand-alone periodontopathic agents. This coinfection of periodontopathic bacteria and active human herpes viruses may constitute a major cause of progression of destructive periodontitis and explain a number of the clinical characteristics of the disease. In this review we discuss the human herpes viruses, their effect on periodontium, interaction with bacteria, various diagnostic method and therapeutic implication.

Keywords Human herpes viruse, bacteria, periodontitis, Epstein–Barr virus, human cytomegalovirus, Herpes simplex virus

How to cite this article: Sanghavi A, Dave D, Nadig P, Sanghavi T, Khanpara N. Human herpes virus: Bacteria and periodontium. J Oral Dis Markers 2016;1:1-5.

3.  Review Article
Dentistry for the critical care patients
Bishnupati Singh, T K Giri, Brajbhushan Mall, M D Chethan, Vallabh Mahadevan, Namrata Sinha
Full Text PDF | Abstract | No of Hits : 865


Oropharyngeal colonization and later translocation will lead to nosocomial pneumonia and other secondary infections. Oral care for the critically ill patients in intensive care units (ICU) demands meticulous maintenance due to the evidence suggestive of secondary systemic infections in the individuals. In the absence of definitive guidelines, and adequate knowledge on the part of nurses imparting oral care to these patients leads to the prevalence of hospital acquired infection and at times mortality. The use of toothbrushes over swabs and use of chlorhexidine mouth rinses helps in reducing the count of microbes. A review of the available literature and compilation of guidelines for delivering oral care after the assessment of dental health will reduce the prevalence of these infections in the ICU.

Keywords Denture care, oral health assessment, oropharyngeal colonization, pediatric care

How to cite this article: Singh B, Giri TK, Mall B, Chethan MD, Mahadevan V, Sinha N. Dentistry for the critical care patients. J Oral Dis Markers 2016;1:1-5.

4.  Case Report
Excision of mucocele using 980 nm diode laser: A case report
Vijayendra Kumar Jain, R Jaiswal Gagan, Jeenal Gupta
Full Text PDF | Abstract | No of Hits : 359


Mucoceles are mucus-filled cavities that may appear in the oral cavity, paranasal sinuses or lacrimal sac giving rise to a round, well-circumscribed transparent, and bluish-colored lesion of different sizes that are typically soft, fluctuant, and painless on palpation and tend to relapse; generally caused due to trauma or obstruction of ducts of the minor salivary gland and found on the lower lip. They may be asymptomatic, but some patients may complain of discomfort, while chewing, swallowing, chewing, or speaking. Different treatment options, including cryosurgery, intralesional corticosteroid injection, micro-marsupialization, marsupialization of the mucocele, conventional surgical removal of the lesión, and most recent laser ablation are available. Laser has secured a special place in soft tissue surgery with less complications and good patient compliance, short treatment time thereby less pain and anxiety, less chances of relapse and good esthetic outcomes. Therefore, this case report highlights the advantages of using diode laser in the treatment of mucocele which has significant recurrent rates.

Keywords Diode laser, mucocele, recurrence

How to cite this article: Jain VK, Gagan RJ, Gupta J. Excision of mucocele using 980 nm diode laser: A case report. J Oral Dis Markers 2016;1:1-3.

5.  Case Report
Prophylactic optic nerve decompression in pediatric craniofacial fibrous dysplasia: To do or not to do?
R Keerthi, Tulasi Nayak
Full Text PDF | Abstract | No of Hits : 287


Fibrous dysplasia (FD) is a pathological condition in which normal bone is replaced by abnormal fibro-connective tissue. Although characterized as a benign condition, it can be large and invasive, causing considerable disfigurement and dysfunction. When faced with such a destructive process in a child, the obvious questions raised are what to do about it and when. We present here a case of craniofacial FD in an 11-year-old boy, in whom the growth in the right orbit had caused swelling, epiphora, proptosis, and pain. The patient was treated with prophylactic optic nerve decompression with excellent results. While deteriorating vision is a definitive indication for optic nerve decompression, the need for a prophylactic treatment is a controversial one. The rate of irreparable loss of vision is well-documented, and the resulting morbidity is one which must be considered in children. We have singularized this case of prophylactic optic nerve to review the various clinical and treatment aspects of craniofacial FD and to specifically debate the viability of prophylactic optic nerve decompression in pediatric craniofacial FD.

Keywords Craniofacial, decompression, optic nerve, pediatric fibrous dysplasia, prophylactic

How to cite this article: Keerthi R, Nayak T. Prophylactic optic nerve decompression in pediatric craniofacial fibrous dysplasia: To do or not to do? J Oral Dis Markers 2016;1:1-6.

6.  Editorial
Sachin C. Sarode, Gargi S. Sarode
Full Text PDF | Abstract | No of Hits : 258


The health science deals with a number of pathologies and their management. The aspects that are associated in dealing with any pathology are demographic, clinical, imaging, microscopic, ultra-microscopic, molecular, therapeutic, prognostic, etc. Sometimes in each of these aspects we find some uniqueness specific for a particular disease, which can be regarded as a “marker” for that disease.

How to cite this article: Sarode SC, Sarode GS. The era of markers in dentistry. J Oral Dis Markers 2016;1:1.

7.  Review Article
Bisphosphonates-osteonecrosis of jaw
Aesha, Shahela Tanveer, Sreeja
Full Text PDF | Abstract | No of Hits : 248


The recent recognition of bisphosphonate use came into use for pathological conditions which includes osteonecrosis of the jaw (ONJ) and other bone diseases. This article highlights about bisphosphonate and its effect and affect on ONJ. Jaw necrosis is a complication associated with conditions such as radiotherapy, severe fungal or bacterial infections, and sarcoidosis or after intravenous bisphosphonate therapy. The intravenous bisphosphonates - pamidronate (Aredia) and zoledronic acid (Zometa), are often used to treat cancer-related hypercalcemia, Paget’s disease, symptoms from solid tumor bone metastasis and osteolytic lesions of multiple myeloma. Bisphosphonate related ONJ has been reported since 2003, in patients taking the drug, more often after dental procedures like extractions, minor surgeries, etc.

Keywords Bisphosphonates, clinical practice, mechanism, osteonecrosis of jaw

How to cite this article: Tanveer S, Aesha, Sreeja. Bisphosphonatesosteonecrosis of jaw. J Oral Dis Markers 2016;1:1-3.

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